First, from Roger Ebert's (if you follow him, you know) incredibly prolific Twitter stream:
Now, maybe the Endup is not in the best neighborhood, but (a) it's not in the Mission District, and (b) the Mission District, while it has some rough patches, is not "Skid Row." Parts of the Tenderloin would qualify as "Skid Row," I guess, and maybe parts of 6th Street, on which the Endup is located, but I think Ebert misread the situation.
Everyone's favorite LA-based casual drug user/snarky advice columnist Coketalk was also in town this weekend. What did she have to say?
A more charitable view, wouldn't you agree?